Sophia Shen

Pronouns: she/her

Current Research Project: Over the past year and a half, I have been investigating proteins involved in Salmonella pathogenesis in the Ko Lab, with the goal of determining the biological importance of secreted proteins in aiding infection. As a biology major, I am particularly interested in protein interactions and the role of genetics in host susceptibility to disease. Through my project with salmonella, I have gained proficiency in laboratory techniques such as western blotting and DNA overexpression, while also strengthening my communication, analytical, and critical thinking skills. Research has been a central part of my Duke experience so far and has strongly influenced my academic interests and the classes that I’m taking. In addition, I am also pursuing a classical archaeology minor, and am eager to gain field experience and explore the intersection between biology and archaeology (bioarchaeology).

How she got involved with research: My first research experience at Duke was through the SURF program the summer after my freshman year. Having no prior background in research, SURF provided a supportive framework that introduced me to the research process while also building essential skills through daily seminars. Through SURF, I had the opportunity to create and present a poster, but more importantly, it connected me to a community of Duke students also passionate about research whom I still keep in touch with today. This positive experience inspired me to continue my research project into sophomore year with the help of the URS Assistantship Grant and seek additional ways to make connections with others and share my work. As a result, I was able to represent Duke at the ACC Meeting of the Minds in Pittsburgh and present at the URS Symposium at the end of the year.