In this research project, I was able to examine the role of a mesencephalic astrocyte derived neurotrophic factor (MANF) in protecting dopaminergic neurons from neurodegeneration in C. elegans. This degeneration is the primary cellular pathology underlying Parkinson’s Disease, a disease whose attributability to genetics alone is only possible in a small minority of cases. This has underscored the importance of elucidating how environmental interactions with biological systems can impact key pathways related to neurodegeneration. I greatly appreciated being able to participate on this project, as it allowed me to pursue research in topics that were interesting to me. Exposure to toxic chemicals is an ever prevalent threat to human and environmental health, and understanding how these exposures affect biological systems is incredibly important to being able to mitigate adverse outcomes. This project was also the foundation for me in developing skills as a researcher. From practical lab skills to efficiently researching information, I would not be where I am today were it not for the mentors I had on this project. Being able to finish the work I did with support from the Dean’s Summer Research Fellowship this past year was truly an honor.